Robert H. Garman, DVM

  • Adjunct Assistant Professor, Department of Pathology

Education & Training

  • DVM, Cornell University 1966

Representative Publications

Garman RH.  Histology of the central nervous system.  Toxicologic Pathology. 39:22-35, 2011

Hale SL, Andrews-Jones L, Jordan WH, Jortner BS, Boyce RW, Boyce JT, Switzer III RC, Butt MT, Garman RH, Jensen K, Krinke G, Little PB.  Modern pathology methods for neural investigations. Toxicologic Pathology. 39:52-57, 2011 

Bolon B, Bradley A, Garman RH, Krinke GJ.:  Useful toxicologic neuropathology references for pathologists and toxicologists. Toxicol Pathol. 2011 Jan;39(1):234-9. Epub 2010 Nov 15. 

Stump DG, Beck MJ, Radovsky A, Garman RH, Freshwater LL, Sheets LP, Marty MS, Waechter JM Jr, Dimond SS, Van Miller JP, Shiotsuka RN, Beyer D, Chappelle AH, Hentges SG. Developmental neurotoxicity study of dietary bisphenol A in Sprague-Dawley rats. Toxicol Sci. 2010 May;115(1):167-82. Epub 2010 Feb 17.

Bolon B, Garman RH, Gundersen HJ, Allan Johnson G, Kaufmann W, Krinke G, Little PB, Makris SL, Mellon RD, Sulik KK, Jensen K. Continuing education course #3: current practices and future trends in neuropathology assessment for developmental neurotoxicity testing. Toxicol Pathol. 2011 Jan;39(1):289-93. Epub 2010 Nov 12. Sills RC and Garman RH.  Gene expression, biomarkers, and glial cells in nervous system diseases.  Toxicologic Pathology. 39:97-98, 2011

Weber K, Garman RH, Germann P-G, Hardisty JF, Krinke G, Millar P and Pardo ID.  Classification of neural tumors in laboratory rodents, emphasizing the rat.  Toxicologic Pathology. 39:129-151, 2011

Garman RH, Jenkins LW, Switzer III RC, Bauman RA, Tong LC, Swauger PV, Parks SA, Dixon CE, Clark RSB, Bayir H, Kagan V, Jackson EK and Kochanek PM.  Blast overpressure injury in rats with body protection is characterized primarily by diffuse axonal injury.  J Neurotrauma. 2011 Jun;28(6):947-59.

Walzer M, Bekersky I, Wanaski S, Collins S, Jortner B, Patterson R, Garman R, Sagar S, Tolbert D.  Oral toxicity of vigabatrin in immature rats: characterization of intramyelinic edema.  Neurotoxicology. 2011 Apr 4. [Epub ahead of print]

Whitney KM, Schwartz Sterman AJ, O'Connor J, Foley GL, Garman RH.  Light microscopic sciatic nerve changes in control beagle dogs from toxicity studies.  Toxicol Pathol. 39(5):835-40, 2011 

Sills RC and Garman RH.  Gene expression, biomarkers, and glial cells in nervous system diseases.  Toxicologic Pathology. 39:97-98, 2011

Garman, RH.  Common histological artifacts in nervous system tissues, Chapter 13 in Fundamental Neuropathology for Pathologists and Toxicologists – Principles and Techniques, Editors: Bolon B and Butt, MT, Wiley, New Jersey, 2011

Manole MD2  Kochanek PM, Foley LM, Hitchens TK, Bay?r H, Alexander H, Garman R, Ma L, Hsia CJ, Ho C, Clark RS. et al:  Polynitroxil Albumin and Albumin Therapy after Pediatric Asphyxial Cardiac Arrest: Effects on Cerebral Blood Flow and Neurological Outcome J Cereb Blood Flow Metab. 2012 Mar;32(3):560-9.

Hemerka J, Wu X, Dixon CE, Garman RH, Exo J, Shellington DK, Blasiole B, Vagni VA, Janesko KL, Xu M, Wisniewski SR, Bayir H, Jenkins LW, Clark R, Tisherman S, Kochanek PM:  Severe brief pressure controlled hemorrhagic shock after traumatic brain injury exacerbates functional deficits and long-term neuropathological damage in mice.  J Neurotrauma. 29:2192-2208 (Aug 10, 2012)

Kaufmann W, Bolon B, Bradley A, Butt M, Czasch S, Garman RH, George C, Gröters S, Krinke G, Little P, McKay J, Narama I,Rao D, Shibutani M, Sills R.:  Proliferative and nonproliferative lesions of the rat and mouse central and peripheral nervous systems. Toxicol Pathol. 2012;40(4 Suppl):87S-157S.

Pardo ID, Garman RH, Weber K, Bobrowski WF, Hardisty JF, Morton D.:  Technical guide for nervous system sampling of the cynomolgus monkey for general toxicity studies. Toxicol Pathol. 2012;40(4):624-36. Epub 2012 Feb 7. 

Rossmeisl JH Jr, Piñeyro P, Sponenberg DP, Garman RH, Jortner BS.:  Clinicopathologic features of intracranial central neurocytomas in 2 dogs.  J Vet Intern Med. 2012 Jan-Feb;26(1):186-91.

Hostnik ET, Kube SA, Jortner B, Hager D, Garman RH.:  Pleomorphic xanthoastrocytoma within the medulla oblongata of a Young Dog.  Vet Pathol. 2014 Mar 31

Calabrese E, Du F, Garman RH, Johnson GA, Riccio C, Tong LC, Long JB.:  Diffusion tensor imaging reveals white matter injury in a rat model of repetitive blast-induced traumatic brain injury.  J Neurotrauma.  2014 Mar 27

Kochanek PM, Dixon CE, Shellington DK, Shin SS, Bay?r H, Jackson EK, Kagan VE, Yan HQ, Swauger PV, Parks SA, Ritzel DV, Bauman R, Clark RS, Garman RH, Bandak F, Ling G, Jenkins LW.:  Screening of biochemical and molecular mechanisms of secondary injury and repair in the brain after experimental blast-induced traumatic brain injury in rats.  J Neurotrauma. 2013 Jun 1;30(11):920-37. doi: 10.1089/neu.2013.2862. Epub 2013 Jun 5.

Bolon B, Garman RH, Pardo ID, Jensen K, Sills RC, Roulois A, Radovsky A, Bradley A, Andrews-Jones L, Butt M, Gumprecht L.:  STP position paper: Recommended practices for sampling and processing the nervous system (brain, spinal cord, nerve and I) during nonclinical general toxicity studies. Toxicol Pathol. 2013; 41(7):1028-48. doi: 10.1177/0192623312474865. Epub 2013 Mar 7

Garman RH, Li AA, Kaufmann W, Auer RN and Bolon B.  Recommended Methods for Brain Processing and Quantitative Analysis in Rodent Developmental Neurotoxicity Studies, Toxicologic Pathology 2016, 44(1)14-42

Fidan E, Lewis J, Kline AE, Garman RH, Henry A, Cheng JP, Bondi CO, Clark RSB, Dezfulian C, Kochanek PM, Kagan VE and Bayir H.  Repetitive mild traumatic brain injury in the developing brain:  effects on long-term functional outcome and neuropathology, J Neurotrauma 2016, 33(7)641-651.

Research Interests

The majority of Dr. Garman’s efforts are concentrated in the arenas of comparative neuropathology and neurotoxicology.  Much of this work is performed in his capacity as a consultant to numerous chemical and pharmaceutical companies and to governmental agencies that are assessing neurotoxic endpoints revealed in safety evaluation studies performed on a variety of animal species.  In addition, Dr. Garman is involved in a number of collaborative research projects on brain ischemia/hypoxia and traumatic brain injury.  These projects are predominantly in collaboration with investigators at the Safar Center for Resuscitation Research at the University of Pittsburgh.